Jackson County is located in the U.S. state of Michigan. The population of the county was 160,366 as of the 2020 Census. Its seat of government is the city of Jackson. The county was set off in 1829 and organized in 1832. It is named for U.S. President Andrew Jackson and considered to be one of Michigan's "Cabinet counties", named for members of Jackson's Cabinet. Jackson County comprises the Jackson, MI Metropolitan Statistical Area. The Jackson County Courthouse was designed by Claire Allen, a prominent southern Michigan architect. Jackson County is also home to the Michigan Whitetail Hall of Fame.